Label-free chemical imaging: Unveiling hidden signatures for molecule-based diagnosis and treatment (Prof. Ji-Xin Cheng)
- Date: Jul 10, 2018
- Time: 02:30 PM - 03:30 PM (Local Time Germany)
- Speaker: Prof. Ji-Xin Cheng
- Photonics Center, Boston University, USA,
- Location: Max-Planck-Institut für Quantenoptik
- Room: New Lecture Hall, Room B 0.32
- Host: MPQ
Various labeling approaches have enabled selective
visualization of cellular structures or biomolecules with high specificity
under a light microscope. Despite great advances made recently, the labeling
approach also has limitations: First, labels may perturb the function of a
biological molecule or structure; Second, the labeling approach offers limited
capacity of discovery because it is only applicable to mapping known species;
Third, delivery of labels to a target could be difficult, especially under in vivo conditions; Fourth, potential
toxicity often prevents the use of labels on human patients. Chemical
microscopy, based on optical spectroscopic signals, opens a way to circumvent
these barriers. I will present various advanced modalities of chemical
microscopy and discoveries of hidden signatures in microstructures, esp. in
living organisms, enabled by chemical microscopy.