Label-free chemical imaging: Unveiling hidden signatures for molecule-based diagnosis and treatment (Prof. Ji-Xin Cheng)

  • Datum: 10.07.2018
  • Uhrzeit: 14:30 - 15:30
  • Vortragende(r): Prof. Ji-Xin Cheng
  • Photonics Center, Boston University, USA,
  • Ort: Max-Planck-Institut für Quantenoptik
  • Raum: New Lecture Hall, Room B 0.32
  • Gastgeber: MPQ
Optical microscopy has been a fundamental tool to life science and materials science since its invention in the 17th century.

Various labeling approaches have enabled selective visualization of cellular structures or biomolecules with high specificity under a light microscope. Despite great advances made recently, the labeling approach also has limitations: First, labels may perturb the function of a biological molecule or structure; Second, the labeling approach offers limited capacity of discovery because it is only applicable to mapping known species; Third, delivery of labels to a target could be difficult, especially under in vivo conditions; Fourth, potential toxicity often prevents the use of labels on human patients. Chemical microscopy, based on optical spectroscopic signals, opens a way to circumvent these barriers. I will present various advanced modalities of chemical microscopy and discoveries of hidden signatures in microstructures, esp. in living organisms, enabled by chemical microscopy.

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